For this one let's analyze:

The sentence is referring to something one man habitually does every evening.

So we need a tense that shows repetition/habitual action.

• Choice A "use to run" is incorrect grammar
• Choice B "are use to run" doesn't make sense
• Choice D "are used to run" is also incorrect grammar
• Only choice C "is used to running" and E "are used to running" work grammatically  

But since it's talking about one man, we need the singular verb "is" to match the subject

Therefore, to best complete the sentence grammatically while conveying habitual repeated action, the right choice is C "is used to running".