The word upheld means to confirm or support something questioned or challenged. 

Therefore, the opposite of upheld would be to reject or overturn something that has been accepted or established.

Looking at the options, the best choice is E. reversed, which means changing something to the opposite direction, position, or course.

The other options are not as good as E.

Held up, maintained, and undercut are not directly related to upholding, and abolished is more specific to the context of laws or institutions.